A.J. Drexel Plasma Institute               Research Fellow, PhD Candidate                              4/2006 – 3/2010

Drexel University, Philadelphia PA

1.    Investigated the induction of DNA damage by non-thermal plasma discharge in mammalian cells by looking at the phosphorylation of H2AX, a DNA damage marker. Additionally, using RNA interference, RT-PCR and molecular biology techniques, studied the ATM/ATR mediated DNA repair pathways in response to DNA damage induced by non-thermal electrical plasma produced reactive oxygen species (ROS).

2.    Studied the mechanisms of Non-thermal plasma induced proliferation of endothelial cells using cell proliferation and migration assays, flow cytometry, to develop non-thermal plasma as a potential novel therapy for growth factor initiated promotion or inhibition of endothelial cell mediated angiogenesis, which is an important target for treating diseases in which there is either poor vascularization (chronic wounds) or abnormal vascularization (malignancies).

3.    Studied the induction of apoptosis in melanoma cancer cells by non-thermal plasma electrical discharge by using Annexin-V/PI, Caspase cleavage and flow cytometry to develop non-thermal plasma as a novel clinical device for cancer treatment.

4.    Investigated the potential long term and short-term toxicity of non-thermal plasma on intact and wounded animal model to develop non-thermal plasma as a potential clinical device for wound sterilization and accelerated wound healing.

5.    Studied the mechanism of blood coagulation by non-thermal atmospheric pressure dielectric barrier discharge to evaluate the use of non-thermal plasma as a potential wound healing device in a clinical or battlefield setting.

Drexel University, Philadelphia PA        Research Fellow, PhD Candidate                      10/2005 – 4/2006 

1.    Studied the anisotropic mobility of non-magnetic spheres in ferrofluid for biotechnological applications like drug delivery, imaging, etc by tracking the motion of nonmagnetic microspheres immersed in ferrofluid under the influence of a uniform external magnetic field.

Drexel University, Philadelphia PA                 Graduate Research Assistant                     4/2005 – 9/2005 

1.    Performed analytical modeling of NMR signal generated by solenoidal microcoil catheters using MATLAB® and elliptical integrals. Characterized the magnetic fields generated by axisymmetric solenoids as a tool for NMR spectroscopy.

1.    Effects of Non-Thermal Plasma on Mammalian Cells, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, G. Friedman, J. Azizkhan-Clifford. PLoS ONE, 21^st January 2011. 6(1): e16270. DOI: 10.1371/journal.pone.0016270. Online First

2.    Live Pig Tissue and Wound Toxicity of Cold Plasma Treatment, D. Dobrynin, A. Wu, S. Kalghatgi, S. Park, N. Shainsky, K. Wasko, G. Fridman, A. Brooks, G. Friedman, A. Fridman. Plasma Medicine, 2011. 1(1): p 93 – 108.

3.    Induction of Apoptosis in Melanoma Cells by Non-Thermal Atmospheric Pressure Plasma, R. Sensenig, S. Kalghatgi, E. Podolsky, E. Cerchar, G. Fridman, A. Shereshevsky, A. Fridman, G. Friedman, A. Brooks, J. Azizkhan-Clifford. Annals of Biomedical Engineering. 3^rd Nov 2010. DOI: 10.1007/s10439-010-0197-x. Online First

4.    Endothelial Cell Proliferation is enhanced by Low Dose Non-Thermal Plasma Treatment through Fibroblast Growth Factor-2 Release, S. Kalghatgi, A. Fridman, G. Friedman, A. Morss Clyne. Annals of Biomedical Engineering, 2010. 38 (3): p 748 – 757

5.    Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M. Balasubramanian, V. N. Vasilets, A. Gutsol, A. Fridman, G. Friedman, IEEE Transactions on Plasma Science, Volume 35, Issue 5, Part 2, Oct. 2007, pp. 1559-1566.

6.    Manipulation of Nonmagnetic Nanobeads in Dilute Ferrofluid, D. Halverson, S. Kalghatgi, B. Yellen, G. Friedman, Journal of Applied Physics, April, 2006, 99 (8): 08P504

7.    Electrical and Heat Flow Simulation of MEMS structures using SPICE, N. Naik, S. Kalghatgi, A. Ghangrekar, S. Shetty, P. R. Apte, International Journal of Computational Engineering Science, 2003, 4(2) p 397-400.

 

1.    Highly Commended Citation for the 2010 Drexel University Best Dissertation Award

2.    Highly Commended Citation for the 2010 Drexel University Excellence in Research Award

3.    Recipient of the 2009 Drexel University Graduate Student Outstanding Service Award

4.    Highly Commended Citation for the 2009 Drexel University Excellence in Research Award

5.    IEEE Student Travel Award, 17^th IEEE International Pulsed Power Conference, Jun 29 – Jul 2 2009, Washington D.C., USA.

6.    Honorable Mention for the PhD level Student Poster Competition at the ASME 2009 Summer Bioengineering Conference, Jun 17 - Jun 21 2009. Lake Tahoe, CA, USA

7.    Invited Talk at the 36^th IEEE International Conference on Plasma Science, May 31 – Jun 4 2009, San Diego, CA, USA.

8.    IEEE Student Travel Award, 36^th IEEE International Conference on Plasma Science, May 31 – Jun 4 2009, San Diego, CA, USA.

9.    Highly Commended Citation for the 2008 Drexel University Excellence in Research Award

10.  Drexel University 2008-09 George Hill Jr. Endowed Fellow

11.  Finalist for the Student Paper Excellence Award at the 61^st Gaseous Electronics Conference, Oct 13^th-17^th 2008, Dallas, TX, USA.

12.  NSF Student Travel Award to attend the 61^st Gaseous Electronics Conference, Oct 13^th-17^th 2008, Dallas, TX

13.  NSF Student Travel Award to attend Gordon Research Conference on Plasma Processing Science, Jul 13^th-18^th 2008 Mt. Holyoke, South Hadley, Massachusetts

14.  Best Student Paper Award at the 36^th IEEE International Conference on Plasma Science, Jun 15^th-19^th 2008, Karlsruhe, Germany

15.  Highly Commended Citation for the 2008 Drexel University Excellence in Research Award

16.  Nominated for 2008 Drexel University Excellence in Teaching Award

17.  Recipient of the 2008 Drexel University International Travel Award

18.  Finalist for Best Student Paper Award at the 35^th IEEE International Conference on Plasma Science, Albuquerque, New Mexico, Jun 16^th - 22^nd 2007

19.  2007 Lee Smith Travelling Fellowship for travel to 18^th International Symposium on Plasma Chemistry, Kyoto, Japan

20.  IEEE Student Travel Award, 34^th IEEE International Conference on Plasma Science, Albuquerque New Mexico, Jun15th - Jun19th 2007.

21.  Honorable mention, 7^th Drexel University Annual Research Day, 2005.

22.  2004 Dean’s Fellowship from Drexel University.

 

1.    DNA Damage In Mammalian Cells By Non-Thermal Atmospheric Pressure Microsecond Pulsed Dielectric Barrier Discharge Plasma Is Not Mediated Via Lipid Peroxidation, S. Kalghatgi, J. Azizkhan-Clifford, A. Fridman, G. Friedman, 37^th IEEE International Conference on Plasma Science (ICOPS), Jun 20^th – Jun 24^th 2010, Norfolk, VA, USA.

2.    Non-Thermal Plasma Enhances Endothelial Cell Proliferation Through Fibroblast Growth Factor-2 Release, S. Kalghatgi, A. Fridman, Alisa Morss-Clyne, G. Friedman, 36th IEEE International Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA (invited).

3.    Effects of Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma Treatment on Mammalian Cells, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, G. Friedman, J. Azizkhan-Clifford, Discovery Day 2009, Drexel University College of Medicine, Oct 7^th 2009, Philadelphia, PA, USA.

4.    Comparison of Different Non-Thermal Plasma Treatments of Mammalian Cells, S. Kalghatgi, C Kelly, E. Cerchar, A Fridman, J Azizkhan-Clifford, G Friedman, 36th IEEE International Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA.

5.    Non-Thermal Plasma Enhances Proliferation of Endothelial Cells, S. Kalghatgi, A. Fridman, Alisa Morss-Clyne, G. Friedman, 2^nd International Conference on Plasma Medicine (ICPM-2), Mar 16^th – Mar 20^th 2009, San Antonio, TX, USA. (Invited)

6.    Toxicity of Direct Non-Thermal Plasma Treatment of Living Tissue, A.S. Wu, S. Kalghatgi, D. Dobrynin, R. Sensenig, G. Fridman, M. Balasubramanian, K. Barbee, A. Fridman, G. Friedman, A.D. Brooks, Trauma and Critical Care 6: Burns/Wound Healing, 4th Annual Academic Surgical Congress (ASC), February 3-6, 2009, Sanibel Harbor Resort, Fort Myers, FL, USA. Presented by: A. S. Wu

7.    Interaction of Non-Thermal Dielectric Barrier Discharge Plasma with DNA inside Cells (Contributed talk and selected as finalist for Student Paper Excellence Award), S. Kalghatgi, C. Kelly, G. Fridman, J. Azizkhan, A. Fridman and G. Friedman. 61^st Annual Gaseous Electronics Conference, Oct 13^th-Oct 17^th, Dallas, TX, USA

8.    Non-Thermal Dielectric Barrier Discharge Plasma Treatment of Endothelial Cells, S. Kalghatgi, G. Fridman, A. Fridman, G. Friedman, A. Morss-Clyne, 30^th International Conference of the IEEE Engineering in Medicine and Biology (EMBC), Aug 20^th-Aug 24^th 2008, Vancouver, Canada. Presented by: Alisa Morss Clyne

9.    Penetration of Direct Non-Thermal Plasma Treatment into Living Cells (Contributed Talk), S. Kalghatgi, C Kelly, G Fridman, A Fridman, J Azizkhan-Clifford, G Friedman, 35th IEEE International Conference on Plasma Science (ICOPS), June 15-19 2008, Karlsruhe, Germany.

10.  Toxicity of Non-Thermal Plasma Treatment of Endothelial Cells (Contributed Talk), S. Kalghatgi, G Fridman, A Fridman, A Morrs-Clyne, G Friedman, 35th IEEE International Conference on Plasma Science (ICOPS), June 15-19 2008, Karlsruhe, Germany. (Best Student Paper Award)

11.  Medical applications of direct strongly non-equilibrium plasmas, G. Friedman, G. Fridman, S. Kalghatgi , R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks, D. Dobrynin, M. Cooper, A. Fridman, A. Gutsol, First International Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX. Presented by: G. Friedman.

12.  Physical and biological mechanisms of plasma interaction with living tissue, A. Fridman, G. Fridman, R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks, D. Dobrynin, S. Kalghatgi, M. Cooper, A. Gutsol, G. Friedman, First International Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX. Presented by: A. Fridman.

13.  Non-thermal atmospheric plasma induces apoptosis in melanoma cancer cells, A. Brooks, G. Fridman, R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, D. Dobrynin, S. Kalghatgi, M. Cooper, A. Fridman, A. Gutsol, G. Friedman, First International Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX. Presented by: A. Brooks.

14.  Medical applications of Floating Electrode Dielectric Barrier Discharge (FE-DBD), G. Fridman, R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks, D. Dobrynin, S. Kalghatgi, M. Cooper, A. Fridman, A. Gutsol, G. Friedman, First International Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX. Presented by: G. Fridman.

15.  Medical Aspects of Plasma Interaction with Living Tissue, G. Friedman, G. Fridman, R. Sensenig, A. Shereshevsky, A.S. Wu, M.L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks, R. Hamilton, D. Dobrynin, S. Kalghatgi, M. Cooper, A. Gutsol, A. Fridman, NATO Advanced Study Institute (ASI), Plasma Assisted Decontamination of Biological and Chemical Agents, September 16-26, 2007, Çesme, Turkey. Presented by: G. Friedman.

16.  Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma (Contributed Talk), S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M. Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, 3^4th IEEE International Conference on Plasma Science, June 17-22 2007, Albuquerque, New Mexico, USA

17.  Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in Melanoma Skin Cancer Cells, G. Fridman, S. Kalghatgi, A. Fridman, A. Gutsol, V. Vasilets, G. Friedman, R. Sensenig, A. Shereshevsky, M. Balasubramanian, M. Jost, A. Brooks, The 34th IEEE International Conference on Plasma Science, June 17-22, 2007, Albuquerque, New Mexico. Presented by: G. Fridman

 

1.    Cell Proliferation Following Non-Thermal Plasma Is Related To Reactive Oxygen Species Induced Fibroblast Growth Factor-2 Release, S. Kalghatgi, A. Fridman, G. Friedman, A. Morss-Clyne. In the Proceedings of the 31^st International Conference of the IEEE Engineering in Medicine and Biology (EMBC), Sep 2^nd- Sep 6^th 2009, Minneapolis, Minnesota, USA.

2.    Low Dose Non-Thermal Plasma Interacts with Mammalian Cells Indirectly through Modification of the Cell Culture Medium, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, J. Azizkhan-Clifford, G. Friedman, Abstracts and full papers, 19th International Symposium on Plasma Chemistry, Jul 26th - July 31^st 2009, Bochum, Germany.

3.    On the Interaction of Non-Thermal Atmospheric Pressure Plasma with Tissues, S. Kalghatgi, C. Kelly, E. Cerchar, R. Sensenig, A. Brooks, A. Fridman, A. Morss-Clyne, J. Azizkhan-Clifford, G. Friedman. in the Proceedings of the 17th IEEE Pulsed Power Conference (PPC), Jun 29 - Jul 2 2009, Washington D.C., USA.

4.    Toxicity of Direct Non-Thermal Atmospheric Pressure Plasma Treatment of Living Tissue, S. Kalghatgi, D. Dobrynin, A. Wu, E. Podolsky, E. Cerchar, G. Fridman, A. Fridman, A. Brooks, K. Barbee, G. Friedman. in the Proceedings of the 17th IEEE Pulsed Power Conference (PPC), Jun 29 - Jul 2 2009, Washington D.C., USA.

5.    Non-Thermal Dielectric Barrier Discharge Plasma Treatment of Endothelial Cells, S. Kalghatgi, G. Fridman, A. Fridman, G. Friedman, A. Morss-Clyne, Proceedings of the 30^th International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Aug 20^th-Aug 24^th 2008, Vancouver, Canada pp. 3578 – 3581.

6.    Penetration of Direct Non-Thermal Plasma Treatment into Living Cells, S. Kalghatgi, C. Kelly, G. Fridman, A. Fridman, J. Azizkhan-Clifford, G. Friedman, Proceedings of the IEEE 35th International Conference on Plasma Science, Jun 15^th – 19^th 2008, Karlsruhe, Germany.

7.    Toxicity of Non-thermal Plasma Treatment of endothelial cells, S. Kalghatgi, G. Fridman, A. Fridman, G. Friedman, A. Morss Clyne, Proceedings of the IEEE 35th International Conference on Plasma Science, Jun 15^th – 19^th 2008, Karlsruhe, Germany.

8.    Toxicity Analysis of Direct Nonthermal Plasma Treatment of Living Tissue, S. Kalghatgi, D. Dobrynin, A. Wu, R. Sensenig, G. Fridman, M. Balasubramanian, K. Barbee, A. Brooks, A. Fridman, G. Friedman, , Proceedings of the IEEE 35th International Conference on Plasma Science, Jun 15^th – 19^th 2008, Karlsruhe, Germany.

9.    Applications of Non Thermal Atmospheric Pressure Plasma in Medicine, S. Kalghatgi, D. Dobrynin, G. Fridman, M. Cooper, G. Nagaraj, L. Peddinghaus, M. Balasubramanian, K. Barbee, A. Brooks, V. Vasilets, A. Gutsol, A. Fridman, and G. Friedman, in NATO Advanced Study Institute on Plasma Assisted Decontamination of Biological and Chemical Agents (Springer, Cesme-Izmir, Turkey, 2007), p. 173.

10.  Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, S. Kalghatgi, M. Balasubramanian, G. Nagaraj, A.S. Wu, A.D. Brooks, G. Fridman, M. Cooper, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, Blood, (ASH Annual Meeting Abstracts) 2007, accepted.

11.  Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge, S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M. Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, In Abstracts and full papers 18th International Symposium on Plasma Science, Aug 26^th-Aug31st, Kyoto University, Kyoto, Japan: Kyoto University, 2007

12.  Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in Melanoma Skin Cancer Cells, G. Fridman, R. Sensenig, S. Kalghatgi, A. Shereshevsky, M. Balasubramanian, A. Gutsol, V. Vasilets, A. Brooks, A. Fridman, G. Friedman, In Abstracts and full papers 18th International Symposium on Plasma Science, Aug 26^th-Aug31st, Kyoto University, Kyoto, Japan: Kyoto University, 2007

13.  Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M. Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, Proceedings of the 34^th International Conference on Plasma Science/16^th Pulsed Power Plasma Symposium, Jun 16 – Jun 22^nd 2007, Albuquerque, New Mexico. pp 1058-1063.

14.  Use of Ferrofluid Patterns as Diffusion Masks, Derek Halverson, Ben Yellen, S. Kalghatgi, G. Friedman, Proceedings of the Materials Research Society Spring Meeting, March 28- April 1 2005, San Francisco.

 

1.    Non-Thermal Plasma Induced Lipid Peroxidation does not lead to DNA Damage, S. Kalghatgi, J. Azizkhan-Clifford, A. Fridman, G. Friedman, Drexel University Research Day, April 15th 2010, Philadelphia, PA, USA (to be presented)

2.    Non-Thermal Plasma Induced DNA Damage Cannot be Attributed to Ozone Alone, S. Kalghatgi, C. Kelly, E. Cerchar, J. Azizkhan-Clifford, A. Fridman, G. Friedman, Drexel University Research Day, April 15th 2010, Philadelphia, PA, USA (to be presented)

3.    DNA Damage In Mammalian Cells By Non-Thermal Atmospheric Pressure Microsecond Pulsed Dielectric Barrier Discharge Plasma Is Not Mediated By Ozone, S. Kalghatgi, C. Kelly, E. Cerchar, J. Azizkhan-Clifford, A. Fridman, G. Friedman, 37^th IEEE International Conference on Plasma Science (ICOPS), Jun 20^th – Jun 24^th 2010, Norfolk, VA, USA (to be presented)

4.    Selectivity Of Non-Thermal Atmospheric Pressure Microsecond Pulsed Dielectric Barrier Discharge Plasma Induced Apoptosis In Malignant Cells Over Normal Cells, S. Kalghatgi, E. Cerchar, J. Azizkhan-Clifford, A. Fridman, G. Friedman, 37^th IEEE International Conference on Plasma Science (ICOPS), Jun 20^th – Jun 24^th 2010, Norfolk, VA, USA (to be presented)

5.    Low Dose Non-Thermal Dielectric Barrier Discharge (DBD) Plasma Enhances Wound Healing In An In Vitro Epithelial Cell Model, Oleg Alekseev, Sameer Kalghatgi, Gary Friedman, and Jane Azizkhan-Clifford, Discovery Day 2009, Drexel University College of Medicine, Oct 7 2009, Philadelphia, PA, USA. (Third Prize).

6.    Cell Proliferation Following Non-Thermal Plasma is Related to Reactive Oxygen Species Induced Fibroblast Growth Factor-2 Release, S. Kalghatgi, A. Fridman, G. Friedman, A. Morss-Clyne. Sep 2^nd- Sep 6 2009, Minneapolis, Minnesota, USA.

7.    Low Dose Non-Thermal Plasma Interacts with Mammalian Cells Indirectly through Modification of the Cell Culture Medium, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, J. Azizkhan-Clifford, G. Friedman, 19th International Symposium on Plasma Chemistry, Jul 26th - July 31^st 2009, Bochum, Germany.

8.    On the Interaction of Non-Thermal Atmospheric Pressure Plasma with Tissues, S. Kalghatgi, C. Kelly, E. Cerchar, R. Sensenig, A. Brooks, A. Fridman, A. Morss-Clyne, J. Azizkhan-Clifford, G. Friedman. 17th IEEE Pulsed Power Conference (PPC), Jun 29th - Jul 2nd 2009, Washington D.C., USA

9.    Toxicity of Direct Non-Thermal Atmospheric Pressure Plasma Treatment of Living Tissue, S. Kalghatgi, D. Dobrynin, A. Wu, E. Podolsky, E. Cerchar, G. Fridman, A. Fridman, A. Brooks, K. Barbee, G. Friedman. 17th IEEE Pulsed Power Conference (PPC), Jun 29th - Jul 2nd 2009, Washington D.C.,

10.  Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma Enhances Endothelial Cell Proliferation Via Fibroblast Growth Factor-2 Release, S. Kalghatgi, A. Fridman, G. Friedman, A. Morss-Clyne, 2009 Summer Bioengineering Conference, Jun 17th - 21st, Lake Tahoe, CA, USA.

11.  Mechanism of Induction of Apoptosis in Melanoma Cancer Cells by Non-Thermal Plasma, S. Kalghatgi, E. Cerchar, G. Fridman, A. Shereshevsky, K. Arjunan, R. Sensenig, E. Podolsky, B. Torabi, A. Fridman, A. Brooks, J. Azizkhan-Clifford, G. Friedman, 36th IEEE International Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA.

12.  Toxicity of direct Non-thermal Plasma Treatment of Living Tissue, D. Dobrynin, S. Kalghatgi, G. Fridman, A. Wu, E. Podolsky, K. Barbee, A. Brooks, A. Fridman, G. Friedman, 36th IEEE International Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA.

13.  Physical and biological mechanisms of plasma interaction with living tissue, G. Fridman, D. Dobrynin, S. Kalghatgi, A. Brooks, G. Friedman, A. Fridman, 36th IEEE International Conference on Plasma Science (ICOPS), May 29th - Jun 4th 2009, San Diego, California, USA.

14.  Toxicity of Low Temperature Plasma Treatment of Living Tissue, D Dobrynin, S. Kalghatgi, G Fridman, A Wu, E Podolsky, K Barbee, A Brooks, G Friedman, A Fridman, 2009 Drexel IEEE Graduate Forum, Technical Poster Symposium, May 4, 2009, Philadelphia, USA.

15.  Induction of Apoptosis by Non-thermal Plasma Treatment of Melanoma Cancer Cells, S. Kalghatgi, K. Arjunan, R. Sensenig, E. Cerchar, E. Podolsky, G. Fridman, B. Torabi, A. Fridman, A. Brooks, J. Azizkhan-Clifford, G. Friedman, 2009 Drexel University Research Day, April 23rd 2009, Philadelphia, PA, USA.

16.  Low Dose Non-Thermal Plasma Enhances Endothelial Cell Proliferation via Release of Fibroblast Growth Factor, S. Kalghatgi, K. Arjunan, A. Fridman, G. Friedman, A. Morss Clyne. 2009 Drexel University Research Day, April 23 2009, Philadelphia, PA, USA.

17.  Mechanisms of Interaction of Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma with Mammalian Cells, S. Kalghatgi, C. Kelly, E. Cerchar, K. Arjunan, A. Fridman, J. Azizkhan-Clifford, G. Friedman, 2009 Drexel University Research Day, April 23rd 2009, Philadelphia, PA, USA.

18.  Toxicity of low temperature plasma treatment of living tissue, D Dobrynin, G Friedman, S. Kalghatgi, G Fridman, A Wu, E Podolsky, K Barbee, A Brooks, A Fridman, 11th Annual Research Day, April 23, 2009, Drexel University, Philadelphia, USA.

19.  Biomedical applications of low temperature plasmas, D Dobrynin, S. Kalghatgi, G Fridman, A Wu, E Podolsky, K Chakravarthy, K Barbee, A Brooks, S Murthy, Y Mukhin, G Friedman, A Fridman, 11th Annual Research Day, April 23, 2009, Drexel University, Philadelphia, USA.

20.  Mechanisms of Interaction of Non-Thermal Plasma with Mammalian Cells, S. Kalghatgi, C. Kelly, E. Cerchar, A. Fridman, J. Azizkhan-Clifford, G. Friedman, ^2nd International Conference on Plasma Medicine (ICPM-2), Mar 1^6th – Mar 2^0th 2009, San Antonio, TX, USA

21.  Induction of Apoptosis by Non-thermal Plasma Treatment of Melanoma Cells, S. Kalghatgi, K. Arjunan, R. Sensenig, E. Cerchar, E. Podolsky, G. Fridman, B. Torabi, A. Fridman, A. Brooks, J. Azizkhan-Clifford, G. Friedman, 2^nd International Conference on Plasma Medicine (ICPM-2), Mar 16^th – Mar 20^th 2009, San Antonio, TX, USA

22.  Non-Thermal Plasma Induces DNA Damage Through the Generation of Long-lived Reactive Oxygen Species, S Kalghatgi, C Kelly, E Cerchar, R Sensing, K Priya-Arjunan, G Fridman, A Fridman, G Friedman, J Clifford-Azizkhan, Drexel University College of Medicine Discovery Day, October 15th 2008, Philadelphia, PA.

23.  Induction of Apoptosis by Non-Thermal Plasma Treatment of Melanoma Cells, R Sensenig, S Kalghatgi, E Cerchar, B Torabi, E Podolsky, K Priya-Arjunan, G Fridman, A Fridman, G Friedman, A Brooks, J Clifford-Azizkhan, Drexel University College of Medicine Discovery Day, October 15th 2008, Philadelphia, PA.

24.  Penetration of Non-Thermal Dielectric Barrier Discharge Plasma Into Living Cells, S. Kalghatgi, C. Kelly, G. Fridman, J. Azizkhan-Clifford Azizkhan, G. Friedman, Gordon Research Conference on Plasma Processing Science, Jul 13-18^th 2008, Mt. Holyoke, South Hadley, Massachusetts.

25.  Physical and Biological Mechanisms of Plasma Interaction with Living Tissue, G Fridman, PI Lelkes, K Barbee, D Dobrynin, M Cooper, H Ayan, VN Vasilets, A Gutsol, A Fridman, AD Brooks, A Shereshevsky, R Sensenig, M Balasubramanian, P Zhu, BD Freedman, C Kelly, J Clifford, S Kalghatgi, G Friedman, 2008 Gordon Research Conference (GRC) on Plasma Processing Science, July 13-18, 2008, Mount Holyoke College, South Hadley, MA, USA.

26.  Toxicity Analysis of Non-Thermal Plasma Treatment of Living Tissue, S. Kalghatgi, D. Dobrynin, R. Sensenig, A. Wu, G. Fridman, K. Barbee, Dr. M. Balasubramanian, Dr. A. Brooks, A. Fridman, G. Friedman, 35th IEEE International Conference on Plasma Science (ICOPS), June 15-19 2008, Karlsruhe, Germany.

27.  Toxicity of Non-thermal Plasma Treatment of Endothelial Cells, S. Kalghatgi, G. Fridman, A. Fridman, G. Friedman, Alisa Morss-Clyne, 35th IEEE International Conference on Plasma Science (ICOPS), June 15-19 2008, Karlsruhe, Germany.

28.  Physical and Biological Mechanisms of Plasma Interaction with Living Tissue, G. Fridman, P. Lelkes, K. Barbee, D. Dobrynin, M. Cooper, Halim Ayan, A. Gutsol, A. Fridman, A. Brooks, A. Shereshevsky, R. Sensenig, M. Balasubramanian, Peimin Zhu, B. Freedman, C. Kelly, J. Azizkhan-Clifford, S. Kalghatgi, G. Friedman, 10^th Annual Drexel University Research Day, April 22^nd 2008, Philadelphia, PA, USA

29.  Treatment of Endothelial Cells by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, S. Kalghatgi, G. Fridman, A. Fridman, G. Friedman, Alisa Morss Clyne, 10^th Annual Drexel University Research Day, April 22^nd 2008, Philadelphia, PA, USA

30.  Penetration of Direct Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma Treatment Into Living Cells, S. Kalghatgi, C. Kelly, G. Fridman, J. Azizkhan-Clifford-Azizkhan, A. Fridman, G. Friedman, 10^th Annual Drexel University Research Day, April 22^nd 2008, Philadelphia, PA, USA

31.  Biomedical Applications of Low Temperature Plasmas, D. Dobrynin, G. Fridman, S. Kalghatgi, A. Wu, R. Sensenig, M. Balasubramanian, K. Barbee, A. Brooks, G. Friedman, Valery Gostev, Yurii Mukhin, A. Fridman, 10^th Annual Drexel University Research Day, April 22^nd 2008, Philadelphia, PA, USA

32.  Induction of apoptosis in Melanoma Cells by Non-Thermal Atmospheric Plasma Discharge, R. Sensenig, S. Kalghatgi, G. Fridman, A. Shereshevsky, A. Brooks, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, SSO's 61st Annual Cancer Symposium, March 13-16, 2008, Chicago. USA

33.  Physical and Biological Mechanisms of Plasma Interaction with Living Tissue, G Fridman, D Dobrynin, S Kalghatgi, M Cooper, A Shereshevsky, P Zhu, C Kelly, R Sensenig, H Ayan, PI Lelkes, K Barbee, VN Vasilets, AD Brooks, M Balasubramanian, BD Freedman, J Clifford, G Friedman, A Gutsol, A Fridman, IEEE Technical Poster Symposium, Drexel University, Philadelphia, March 7, 2008.

34.  Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, G. Nagaraj, S. Kalghatgi, A. Wu, G. Fridman, M. Cooper, M. Peddinghaus, M. Balasubramanian, A. Brooks, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, American Society of Hematology Annual Meeting, Dec 7-11, 2007. Atlanta. USA

35.  Medical Applications of Floating Electrode Dielectric Barrier Discharge, G. Fridman, R. Sensenig, A. Shereshevsky, L. Peddinghaus, M. Balasubramanian, M. Jost, A. Brooks, D. Dobrynin, S. Kalghatgi, H. Ayan, M. Cooper, A. Fridman, A. Gutsol, V. Vasilets, G. Friedman, The Translational Research in Biomedical Engineering Poster Competition, Drexel University, Philadelphia, October 26, 2007.

36.  Mechanism of Blood Coagulation by Non-Thermal (Cold) Atmospheric Pressure Dielectric Barrier Discharge Plasma, S. Kalghatgi, G. Fridman, G. Nagaraj, M. Cooper, M. Balasubramanian, A. Brooks, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, First International Conference on Plasma Medicine (ICPM-1), October 15th - 18th, 2007, Corpus Christi, TX.

37.  Sterilization of Living Human and Animal Tissue by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, G. Fridman, M. Cooper, D. Dobrynin, H. Ayan, A. Fridman, A. Gutsol, V. Vasilets, S. Kalghatgi, G. Friedman, A. Shereshevsky, A. Brooks, M. Peddinghaus, M. Balasubramanian, NATO Advanced Study Institute (ASI), Plasma Assisted Decontamination of Biological and Chemical Agents, September 16-26, 2007, Çesme, Turkey.

38.  Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in Melanoma Skin Cancer Cells, G. Fridman, S. Kalghatgi, R. Sensenig, A. Shereshevsky, R. Stoddard, G. Friedman, A. Gutsol, V. Vasilets, A. Fridman, A.D. Brooks, NATO Advanced Study Institute (ASI), Plasma Assisted Decontamination of Biological and Chemical Agents, September 16-26, 2007, Çesme, Turkey.

39.  Devices and Technological Aspects of Plasma-Medical Systems, G. Friedman, G. Fridman, H. Ayan, S. Kalghatgi, A. Fridman, A. Gutsol, NATO Advanced Study Institute (ASI), Plasma Assisted Decontamination of Biological and Chemical Agents, September 16-26, 2007, Çesme, Turkey.

40.  Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, S. Kalghatgi, G. Fridman, M. Cooper, G. Nagaraj, M. Peddinghaus, M. Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, G. Friedman, 18^th International Symposium on Plasma Chemistry, Aug 26^th – Aug 31^st 2007, Kyoto, Japan

41.  Non-Equilibrium Dielectric Barrier Discharge Plasma Promoting Apoptotic Behavior in Melanoma Skin Cancer Cells, G. Fridman, R. Sensenig, S. Kalghatgi, A. Shereshevsky, M. Balasubramanian, A. Gutsol, V. Vasilets, A. Brooks, A. Fridman, G. Friedman, 18th International Symposium on Plasma Chemistry, August 26 - 31, 2007, Kyoto, Japan.

42.  Wound Sterilization and Promoted Healing using Non-thermal Atmospheric Pressure Plasma, Charles Marine, G. Fridman, Mogeega Cooper, A. Fridman, A. Gutsol, V. Vasilets, S. Kalghatgi, G. Friedman, STAR Scholars Program, Pennoni Honors College, Drexel University, August 15th, 2007.

43.  Floating Electrode Dielectric Barrier Discharge Initiates Apoptosis in Melanoma Skin Cancer Cells, G. Fridman, S. Kalghatgi, R. Sensenig, A. Shereshevsky, Rick Stoddard, G. Friedman, A. Gutsol, V. Vasilets, A. Fridman, A. Brooks, Drexel University Ninth Annual Research Innovation Scholarship and Creativity (RISC) Day, April 17, 2007, Drexel University, Philadelphia, USA.

44.  Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, S. Kalghatgi, M. Cooper, G. Fridman, Lisa Peddinghaus, G. Nagaraj, M. Balasubramanian, V. Vasilets, A. Gutsol, A. Fridman, and G. Friedman, Drexel University Ninth Annual Research Innovation Scholarship and Creativity (RISC) Day, April 17, 2007, Drexel University, Philadelphia, USA.

45.  Sterilization of Living Human and Animal Tissue by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma, G. Fridman, M. Cooper, D. Dobrynin, Halim Ayan, A. Fridman, A. Gutsol, V. Vasilets, S. Kalghatgi, G. Friedman, A. Shereshevsky, A. Brooks, M. Peddinghaus, M. Balasubramanian, Drexel University Ninth Annual Research Innovation Scholarship and Creativity (RISC) Day, April 17, 2007, Drexel University, Philadelphia, USA

46.  On Anisotropic mobility of non-magnetic microspheres in Ferrofluid, S. Kalghatgi, Derek Halverson, Mario Baden, Gennady Friedman, Drexel University Annual Research Day, April 2005 Drexel University, Philadelphia

47.  Manipulation of Non-Magnetic Materials in Ferrofluid Containing Media, Derek Halverson, Ben Yellen, S. Kalghatgi, Gennady Friedman, Drexel University Annual Research Day, April 2005 Drexel University, Philadelphia (Received a Honorable mention from the ECE Department).

 

1.    Plasma treatment for growth factor release from cells and tissues. S. Kalghatgi, A. Fridman, G. Friedman, Alisa Morss Clyne. March 16th 2009 - Patent electronically filed with the United States Patent & Trademark Office (U. S. Provisional Patent Application Serial No. 61/160,496)

 

Laboratory Skills: RT2-PCR, Microarray analysis, Genomic Sequencing, Confocal Microscopy, si/sh RNAi assays, Plasmid DNA extraction, Gel Electrophoresis, Immunoblotting (Western Blots), ELISA’s, Cell Culture, Cell Proliferation and Migration Assays, Apoptosis (caspase cleavage, TUNEL, Annexin V/PI), Flow Cytometry, FACS analysis, Immunohistochemistry, Histology, Fluorescence Microscopy, Immunofluorescence, Cytotoxicity Assays, Lipid Peroxidation Assays, Comet Assay, in-vivo animal studies (porcine and mice models), FTIR-ATR, SEM.

Software Tools: GraphPad Graphing & Statistics, Protein Quantification, Gel Imaging, MS Office, MATLAB, PSpice, ImagePro.

Research Writing: Journal and Conference manuscripts, IRB and IACUC protocols, grant proposals and patents

Reviewer                     IEEE Transactions on Plasma Science                                         10/2007 – Present

Treasurer                    Graduate Student Association (GSA)                                                 6/2008 – 6/2009

Responsible for allocating and managing a budget of $100,000 for all the daughter Graduate student
organizations spread over three different Drexel University campuses. Negotiated successfully with the Drexel University to award 100% Health Insurance to all Full-Time PhD Students, Implemented a campaign and fundraiser towards increasing awareness for recycling on campus, Oversight and planning of Graduate Student Day handed over to the GSA in its entirety.

Vice President            Engineering Graduate Association (EGA)                                         6/2006 – 6/2008

Leader in a group of 500 engineering graduate students that promotes collaboration between engineering departments. Organized various seminars, socials, outings and sporting events allowing students to share research ideas, socialize in a large peer group and become actively involved in various activities on campus.

Secretary                    Engineering Graduate Association (EGA)                                          6/2005 – 6/2006

Drexel University, Philadelphia PA                        Teaching Assistant                              1/2006 – Present

Electrical Engineering Department: Taught undergraduate level engineering courses at Drexel University Electrical and Computer Engineering Department. My primary role was to conduct lab sessions, hold recitations, grade home works, quizzes and lab reports, and teach a few lectures for the following courses

Fundamentals of Intelligent Systems (Winter 06, Spring 06); Transform Methods and Filtering (Winter 07); Electronic Devices (Spring 07, Fall 07); Laboratory 4 (Summer 07, Winter 08, Summer 08); Laboratory 1 (Spring 08); Electromagnetic Fields and Waves (Fall 08); Laboratory 2 (Winter 09); Solid State Devices (graduate course) (Fall 09).

 

Institute of Electrical and Electronic Engineers (IEEE)                                              June 2004 – Present

American Association for Advancement of Science (AAAS)                                          Jan 2008 – Present

Founding member of the International Society of Plasma Medicine (ISPM)                                Mar 2009